Western blot All lanes: DCXR antibody at 4.74ug/ml Lane 1: MCF-7 whole cell lysate Lane 2: Hela whole cell lysate Lane 3: A549 whole cell lysate Lane 4: 293T whole cell lysate Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 45 kDa Observed band size: 45 kDa
VRK1 Antibody
CSB-PA857466DSR1HU
ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetVRK1
Overview
- SupplierCusabio
- Product NameVRK1 Antibody
- Delivery Days Customer20
- ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID7443
- Target nameVRK1
- Target descriptionVRK serine/threonine kinase 1
- Target synonymsPCH1; PCH1A; serine/threonine-protein kinase VRK1; vaccinia related kinase 1; vaccinia virus B1R-related kinase 1
- HostRabbit
- IsotypeIgG
- Protein IDQ99986
- Protein NameSerine/threonine-protein kinase VRK1
- Scientific DescriptionSerine/threonine kinase involved in Golgi disassembly during the cell cycle: following phosphorylation by PLK3 during mitosis, required to induce Golgi fragmentation. Acts by mediating phosphorylation of downstream target protein. Phosphorylates \\\Thr-18\\\ of p53/TP53 and may thereby prevent the interaction between p53/TP53 and MDM2. Phosphorylates casein and histone H3. Phosphorylates BANF1: disrupts its ability to bind DNA, reduces its binding to LEM domain-containing proteins and causes its relocalization from the nucleus to the cytoplasm. Phosphorylates ATF2 which activates its transcriptional activity.
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC12352203