VRT-325 [815592-21-3]

MedChem Express

VRT-325 [815592-21-3]

5

815592-21-3

Research Use Only

C27H34N4O4S

510.65

VRT-325 is a novel small molecule discovered by screening a compound library designed to address the genetic defect in cystic fibrosis (CF) caused by the deltaF508 mutation in CFTR. VRT-325 belongs to a class of compounds that promote deltaF508-CFTR efflux from the endoplasmic reticulum and restores chloride transport levels in epithelial cells of CF-derived bronchi[1].

CC(N1CCN(CC1)S(=O)(C2=CC=C(C=C2)OC)=O)C3=NC(OC4CCCCC4)=C5C=CC=CC5=N3

12352200