VRT-534 [926664-32-6]

MedChem Express

VRT-534 [926664-32-6]

14

926664-32-6

Research Use Only

98.32

C25H24ClN3O4S

497.99

VRT-534 (Compound 3) is a chemical chaperone targeting connexin 26 (Cx26). Vrt-534 exhibits dose-responsive binding to recombinant WT Cx26 and mutant Cx26 K188N with EC50s of 19 and 5 microM, respectively. Vrt-534 can be used in research related to hearing impairment[1].

O=C(C1(C2=CC=C3C(OCO3)=C2)CC1)NC(S4)=NC=C4[C@@H](N(CC5)C[C@@H]5O)C(C=CC=C6)=C6Cl

-20°C,2°C to 8°C

12131703