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VU 0285683 [327056-22-4]

VU 0285683 [327056-22-4]

Research Use Only
T23509
TargetMol Chemicals
CAS Number327056-22-4
Product group Chemicals
Estimated Purity99.80%
Molecular Weight266.23
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    VU 0285683
  • Delivery Days Customer
    9
  • CAS Number
    327056-22-4
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    VU 0285683
  • Estimated Purity
    99.80%
  • Molecular Formula
    C14H7FN4O
  • Molecular Weight
    266.23
  • Scientific Description
    VU 0285683 is a specific negative allosteric modulator of mGluR5 with a high affinity for the MPEP binding site. VU 0285683 shows anxiolytic-like activity.
  • Shelf life instruction
    3 years
  • SMILES
    C(#N)C=1C=C(C=C(F)C1)C2=NC(=NO2)C3=CC=CC=N3
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

References

  • Discovery of novel allosteric modulators of metabotropic glutamate receptor subtype 5 reveals chemical and functional diversity and in vivo activity in rat behavioral models of anxiolytic and antipsychotic activity. Rodriguez AL et al., 2010 Dec, Mol Pharmacol
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