VU 0365114

MedChem Express

VU 0365114 [1208222-39-2]

10

1208222-39-2

Research Use Only

99.41

C22H14F3NO3

397.35

VU 0365114 is a selective mAChR M 5 positive allosteric modulator, with an EC 50 of 2.7 microM, and >30 microM for M1, M2, M3 and M4 receptors. VU 0365114 increases insulin secretion stimulated by ACh in human beta-cells [1] [2] [3] .

O=C1N(C2=CC=C(OC(F)(F)F)C=C2C1=O)CC3=CC=C(C4=CC=CC=C4)C=C3

-20°C,2°C to 8°C

12352200