VU0360172 [1310012-12-4]
HY-120589
CAS Number1310012-12-4
Product group Chemicals
Estimated Purity98.07
Molecular Weight294.32
Overview
- SupplierMedChem Express
- Product NameVU0360172 [1310012-12-4]
- Delivery Days Customer10
- CAS Number1310012-12-4
- CertificationResearch Use Only
- Estimated Purity98.07
- Molecular FormulaC18H15FN2O
- Molecular Weight294.32
- Scientific DescriptionVU0360172 is a potent and selective mGlu5 receptor positive allosteric modulator with an EC50 value of 16 nM and a Ki of 195 nM, respectively. VU0360172 stimulates polyphosphoinositide (PI) hydrolysis in vivo, which is abrogated in mGlu5 receptors gene deleted mice[1]. VU0360172 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
- SMILESO=C(NC1CCC1)C2=CC=C(N=C2)C#CC3=CC=CC(F)=C3
- Storage Instruction2°C to 8°C
- UNSPSC12352200