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ProductsBack/VU0467485 [1451994-10-7]

VU0467485 [1451994-10-7]

HY-120184
MedChem Express
CAS Number1451994-10-7
Product group Chemicals
Estimated Purity99.29
Molecular Weight360.41
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Overview

  • Supplier
    MedChem Express
  • Product Name
    VU0467485 [1451994-10-7]
  • Delivery Days Customer
    10
  • CAS Number
    1451994-10-7
  • Certification
    Research Use Only
  • Estimated Purity
    99.29
  • Molecular Formula
    C17H17FN4O2S
  • Molecular Weight
    360.41
  • Scientific Description
    VU0467485 (AZ13713945) is a potent, selective, and orally bioavailable muscarinic acetylcholine receptor 4 (M4) positive allosteric modulator (PAM). VU0467485 (AZ13713945) potentiates activity of ACh at M4 with EC50s of 26.6 nM and 78.8 nM at rat and human M4 receptors, respectively. VU0467485 (AZ13713945) shows selectivity for M4 over human and rat M1/2/3/5. VU0467485 (AZ13713945) displays moderate to high CNS penetration. VU0467485 (AZ13713945) has antipsychotic-like activity[1].
  • SMILES
    O=C(C1=C(N)C2=C(C)C(C)=NN=C2S1)NCC3=CC=C(OC)C(F)=C3
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

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