Bio-Connect

VU0477886 [1926222-30-1]

HY-115796
MedChem Express
CAS Number1926222-30-1
Product group Chemicals
Molecular Weight392.80
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Overview

  • Supplier
    MedChem Express
  • Product Name
    VU0477886 [1926222-30-1]
  • Delivery Days Customer
    9
  • CAS Number
    1926222-30-1
  • Certification
    Research Use Only
  • Molecular Formula
    C20H13ClN4O3
  • Molecular Weight
    392.80
  • Scientific Description
    VU0477886 is a metabotropic glutamate receptor subtype 4 (mGlu4) positive allosteric modulator with potent activating activity on mGlu4 (EC50 = 95nM, 89% Glu Max), good pharmacokinetic characteristics (brain: plasma Kp = 1.3), and significant therapeutic efficacy in Parkinsons disease models.
  • SMILES
    O=C(C1=NC=CC=C1N)NC2=CC=C(N3C(C4=C(C3=O)C=CC=C4)=O)C(Cl)=C2
  • UNSPSC
    12352200