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VU10010 [633283-39-3]

HY-14563
MedChem Express
CAS Number633283-39-3
Product group Chemicals
Estimated Purity98.70
Molecular Weight345.85
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Overview

  • Supplier
    MedChem Express
  • Product Name
    VU10010 [633283-39-3]
  • Delivery Days Customer
    10
  • CAS Number
    633283-39-3
  • Certification
    Research Use Only
  • Estimated Purity
    98.70
  • Molecular Formula
    C17H16ClN3OS
  • Molecular Weight
    345.85
  • Scientific Description
    VU10010 is a potent, highly selective and allosteric M4 mAChR potentiator with an EC50 of 400 nM. VU10010 binds to an allosteric site on M4 mAChR and increases affinity for acetylcholine and coupling to G proteins. VU10010 increases carbachol-induced depression of transmission at excitatory but not inhibitory synapses in the hippocampus[1].
  • SMILES
    O=C(C1=C(N)C2=C(C)C=C(C)N=C2S1)NCC3=CC=C(Cl)C=C3
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200

MSDS

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