VU590 (dihydrochloride) [1783987-83-6]

MedChem Express

VU590 (dihydrochloride) [1783987-83-6]

10

1783987-83-6

Research Use Only

C24H34Cl2N4O7

561.46

VU590 dihydrochloride is a potent and moderately selective ROMK (Kir1.1) inhibitor, with an IC50 of 290 nM. VU590 also inhibits Kir7.1, with an IC50 of 8 microM. VU590 dihydrochloride is not a good probe of ROMK function in the kidney[1][2].

O=[N+](C1=CC=C(CN2CCOCCOCCN(CCOCC2)CC3=CC=C([N+]([O-])=O)C=C3)C=C1)[O-].Cl.Cl

RT

12352200