Belnacasan
M3532
CAS Number273404-37-8
Product group Chemicals
Estimated Purity0.9968
Molecular Weight509.0
Overview
- SupplierAbMole BioScience
- Product NameVX-765 (Belnacasan)
- Delivery Days Customer9
- CAS Number273404-37-8
- Category SupplierChemical
- CertificationResearch Use Only
- Estimated Purity0.9968
- Molecular FormulaC24H33ClN4O6
- Molecular Weight509.0
- Scientific DescriptionBelnacasan (VX-765) is a potent and selective inhibitor of caspase-1 with Ki of 0.8 nM. Belnacasan (VX-765) inhibits the release of LPS-induced IL-1bèta and IL-18 by human PBMCs with an IC50 of ~0.7 uM.
- SMILESCCOC1OC(=O)CC1NC(=O)C2CCCN2C(=O)C(NC(=O)C3=CC(=C(N)C=C3)Cl)C(C)(C)C
- Storage InstructionPowder-20°C
- UNSPSC12352200