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Belnacasan

M3532
AbMole BioScience
CAS Number273404-37-8
DownloadDatasheet
Product group Chemicals
Estimated Purity0.9968
Molecular Weight509.0
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Overview

  • Supplier
    AbMole BioScience
  • Product Name
    VX-765 (Belnacasan)
  • Delivery Days Customer
    9
  • CAS Number
    273404-37-8
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Estimated Purity
    0.9968
  • Molecular Formula
    C24H33ClN4O6
  • Molecular Weight
    509.0
  • Scientific Description
    Belnacasan (VX-765) is a potent and selective inhibitor of caspase-1 with Ki of 0.8 nM. Belnacasan (VX-765) inhibits the release of LPS-induced IL-1bèta and IL-18 by human PBMCs with an IC50 of ~0.7 uM.
  • SMILES
    CCOC1OC(=O)CC1NC(=O)C2CCCN2C(=O)C(NC(=O)C3=CC(=C(N)C=C3)Cl)C(C)(C)C
  • Storage Instruction
    Powder-20°C
  • UNSPSC
    12352200

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