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W-54011 [405098-33-1]

W-54011 [405098-33-1]

T17250
TargetMol Chemicals
CAS Number405098-33-1
DownloadMSDS
Product group Chemicals
Estimated Purity0.9562
Molecular Weight493.08
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    W-54011 [405098-33-1]
  • Delivery Days Customer
    4
  • CAS Number
    405098-33-1
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    W-54011
  • Estimated Purity
    0.9562
  • Molecular Formula
    C30H37ClN2O2
  • Molecular Weight
    493.08
  • Scientific Description
    W-54011 is a potent non-peptide C5a receptor antagonist. W-54011 inhibits the binding of 125I-labeled C5a to human neutrophils (Ki = 2.2 nM). W-54011 inhibits C5a-induced intracellular Ca2+ mobilization, chemotaxis, and generation of ROS in human neutrophils (IC50s = 3.1 nM, 2.7 nM, and 1.6 nM, respectively).
  • Shelf life instruction
    3 years
  • SMILES
    Cl.COc1ccc2CCCC(C(=O)N(Cc3ccc(cc3)N(C)C)c3ccc(cc3)C(C)C)c2c1
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

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