WAY-181187 (hydrochloride)

MedChem Express

WAY-181187 (hydrochloride) [554403-08-6]

14

554403-08-6

Research Use Only

C15H14Cl2N4O2S2

417.33

WAY-181187 (SAX-187) hydrochloride is a potent and selective full 5-HT6 receptor agonist with a Ki of 2.2 nM and an EC50 of 6.6 nM[1]. WAY-181187 hydrochloride mediates 5-HT6 receptor-dependent signal pathways, such as cAMP, Fyn and ERK1/2 kinase, as specific agonist[2].

NCCC1=CN(S(=O)(C2=C(Cl)N=C3SC=CN32)=O)C4=C1C=CC=C4.[H]Cl

12352200