WCA-814
HY-149914
Overview
- SupplierMedChem Express
- Product NameWCA-814 [2951858-45-8]
- Delivery Days Customer14
- CertificationResearch Use Only
- Molecular FormulaC46H53ClN10O5
- Molecular Weight861.43
- Scientific DescriptionWCA-814 is an androgen receptor (AR) antagonist-Hsp90 inhibitor conjugate. WCA-814 induces the degradation of full-length and AR-V7. WCA-814 has cytotoxic effect in prostatic cancer cells (IC50: 171.2 nM, 26.5 nM for LNCaP, 22Rv1 cell)[1].
- SMILESCC(C1=C(C=C(C(C2=NNC(N2C3=CC=C(C=C3)CN4CCN(CC4)CC5CCN(CC5)C6=CC=C(N=N6)C(N[C@H]7CC[C@@H](CC7)OC8=CC(Cl)=C(C=C8)C#N)=O)=O)=C1)O)O)C
- UNSPSC12131703