Bio-Connect

WCA-814

HY-149914
MedChem Express
Molecular Weight861.43
Product group Chemicals
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Overview

  • Supplier
    MedChem Express
  • Product Name
    WCA-814 [2951858-45-8]
  • Delivery Days Customer
    14
  • Certification
    Research Use Only
  • Molecular Formula
    C46H53ClN10O5
  • Molecular Weight
    861.43
  • Scientific Description
    WCA-814 is an androgen receptor (AR) antagonist-Hsp90 inhibitor conjugate. WCA-814 induces the degradation of full-length and AR-V7. WCA-814 has cytotoxic effect in prostatic cancer cells (IC50: 171.2 nM, 26.5 nM for LNCaP, 22Rv1 cell)[1].
  • SMILES
    CC(C1=C(C=C(C(C2=NNC(N2C3=CC=C(C=C3)CN4CCN(CC4)CC5CCN(CC5)C6=CC=C(N=N6)C(N[C@H]7CC[C@@H](CC7)OC8=CC(Cl)=C(C=C8)C#N)=O)=O)=C1)O)O)C
  • UNSPSC
    12131703