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ProductsBack/WDFY3 Antibody

Immunohistochemistry of paraffin-embedded human gastric cancer using CSB-PA809030LA01HU at dilution of 1:100

Immunohistochemistry of paraffin-embedded human gastric cancer using CSB-PA809030LA01HU at dilution of 1:100

Immunohistochemistry of paraffin-embedded human gastric cancer using CSB-PA809030LA01HU at dilution of 1:100

WDFY3 Antibody

CSB-PA809030LA01HU

ApplicationsImmunoFluorescence, ELISA, ImmunoHistoChemistry

Product group Antibodies

ReactivityHuman

TargetWDFY3

Overview

Supplier
Cusabio
Product Name
WDFY3 Antibody
Delivery Days Customer
20
Applications
ImmunoFluorescence, ELISA, ImmunoHistoChemistry
Certification
Research Use Only
Clonality
Polyclonal
Conjugate
Unconjugated
Gene ID23001
Target name
WDFY3
Target description
WD repeat and FYVE domain containing 3
Target synonyms
ALFY, BCHS, MCPH18, ZFYVE25, WD repeat and FYVE domain-containing protein 3, autophagy-linked FYVE protein
Host
Rabbit
Isotype
IgG
Protein IDQ8IZQ1
Protein Name
WD repeat and FYVE domain-containing protein 3
Scientific Description
Required for selective autophagy (aggrephagy) but not for autophagic degradation of bulk cytospol in response to starvation. Involved in the formation and degradation of cytoplasmic polyubiquitin-containing bodies (p62 bodies, ALIS/aggresome-like induced structures). May play a role as adaptor or scaffolding protein by promoting the association of the E3-like ligase ATG12-ATG5-ATG16L and LC3 to ubiquitinated target substrate. The association with GABARAP is required for its recruitment to LC3B-positive p62 bodies suggesting a role in targeting certain p62 structures for clearance. Involved in midbody ring degradation.
Reactivity
Human
Storage Instruction
-20°C or -80°C
UNSPSC
41116161

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