WDR5-IN-1

MedChem Express

WDR5-IN-1 [2408842-51-1]

10

2408842-51-1

Research Use Only

98.0

C30H31FN4O3

514.59

WDR5-IN-1 is a potent and selective WD repeat domain 5 (WDR5) inhibitor, with a K d of 50 of 2.2 nM. WDR5-IN-1 diminishes MYC recruitment at WDR5-displaced genes and exhibits potent anti-proliferative effects in CHP-134 (neuroblastoma) and Ramos (Burkitts lymphoma) lines [1] .

COC1=CC(OC)=CC(CN2C(C(C=C(CN3C(N(C)C=C3)=N)C=C4C5=C(C)C=C(F)C=C5)=C4CC2)=O)=C1

-20°C,2°C to 8°C

12352200