WDR5-IN-4 [2407457-36-5]

MedChem Express

WDR5-IN-4 [2407457-36-5]

10

2407457-36-5

Research Use Only

98.13

C25H22Cl2FN5O

498.38

WDR5-IN-4 (Compound C6) is a WIN site inhibitor of chromatin-associated WD repeat domain 5 protein (WDR5), Kd The value is 0.1 nM. WDR5-IN-4 is able to displace WDR5 from chromatin and reduce the expression of related genes, causing translation inhibition and nucleolar stress. Has anti-cancer effects [1][1].

ClC1=CC=C(CNC(C2=CC(CN3C(N(C)C=C3)=N)=CC(C4=C(C)N=C(F)C=C4)=C2)=O)C=C1Cl

-20°C,2°C to 8°C

12352200