
Immunofluorescence staining of U251 cells with CSB-PA764810LA01HU at 1:173, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
WDR59 Antibody
CSB-PA764810LA01HU
ApplicationsImmunoFluorescence, Western Blot, ELISA
Product group Antibodies
ReactivityHuman
TargetWDR59
Overview
- SupplierCusabio
- Product NameWDR59 Antibody
- Delivery Days Customer20
- ApplicationsImmunoFluorescence, Western Blot, ELISA
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID79726
- Target nameWDR59
- Target descriptionWD repeat domain 59
- Target synonymsCDW12, FP977, p90-120, GATOR2 complex protein WDR59, CDw12 antigen, GATOR complex protein WDR59, WD repeat-containing protein 59
- HostRabbit
- IsotypeIgG
- Protein IDQ6PJI9
- Protein NameGATOR2 complex protein WDR59
- Scientific DescriptionAs a component of the GATOR subcomplex GATOR2, functions within the amino acid-sensing branch of the TORC1 signaling pathway. Indirectly activates mTORC1 and the TORC1 signaling pathway through the inhibition of the GATOR1 subcomplex (PubMed:23723238). It is negatively regulated by the upstream amino acid sensors SESN2 and CASTOR1 (PubMed:25457612, PubMed:27487210).
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC41116161


