WEHI-3773

MedChem Express

WEHI-3773

5

CHEMICAL,general_chemicals_reagents

Research Use Only

C30H22N10O2S2

618.69

WEHI-3773 is an inhibitor of the interaction between VDAC2 and BAK or BAX. WEHI-3773 inhibits BAX-mediated Apoptosis by blocking the VDAC2-mediated recruitment of BAX to mitochondria. Conversely, WEHI-3773 promotes BAK-mediated Apoptosis by limiting the inhibitory sequestration of BAK by VDAC2. WEHI-3773 is promising for research in the field of anti-cancer [1].

CSC1=CC=C(N2C(/C(C3=C(N)C(C#N)=C(N)N=C32)=C4C(N(C5=CC=C(SC)C=C5)C6=NC(N)=C(C#N)C(N)=C6/4)=O)=O)C=C1

12352005