WEHI-9625

AbMole BioScience

WEHI-9625

9

2595314-46-6

Research Use Only

C34H27NO5S2

593.71

WEHI-9625 is a first-in-class tricyclic sulfone, first-in-class inhibitor of apoptosis with an EC50 of 69 nM. WEHI-9625 binds to VDAC2 and promotes its ability to inhibit apoptosis driven by mouse BAK. WEHI-9625 is completely inactive against both human BAK and the closely related apoptosis effector BAX.

12352200