WJ35435 [1620054-84-3]
HY-117688
CAS Number1620054-84-3
Product group Chemicals
Molecular Weight351.40
Overview
- SupplierMedChem Express
- Product NameWJ35435 [1620054-84-3]
- Delivery Days Customer9
- CAS Number1620054-84-3
- CertificationResearch Use Only
- Molecular FormulaC20H21N3O3
- Molecular Weight351.40
- Scientific DescriptionWJ35435 is a dual-targeted anticancer hybrid that induces anti-HDAC (in particular HDAC1 and HDAC6) and anti-topoisomerase I activities that causes DNA damage associated with a low DNA repair capability and induces cell cycle arrest at G1- and G2-phase to apoptosis. WJ35435 induces histone H3 acetylation and phosphorylation, alpha-tubulin acetylation and gamma-H2AX formation to achieve anti-HDAC effect. WJ35435 is promising for research of cancer[1].
- SMILESO=C(C1=CC=CC2=CC3=C(N=C21)C=CC=C3)NCCCCCC(NO)=O
- UNSPSC12352200