Bio-Connect

WK499

HY-149522
MedChem Express
Molecular Weight498.33
Product group Chemicals
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Overview

  • Supplier
    MedChem Express
  • Product Name
    WK499
  • Delivery Days Customer
    14
  • Certification
    Research Use Only
  • Molecular Formula
    C21H20BrN7O3
  • Molecular Weight
    498.33
  • Scientific Description
    BCL6-IN-10 (Compound WK499) is a BCL6 inhibitor. BCL6-IN-10 interrupts the binding of BCL6 to SMRT protein. BCL6-IN-10 induces cell apoptosis, cell cycle arrest and DNA damage. BCL6-IN-10 inhibits AML cell proliferation (IC50s: 0.91, 1.63, 1.026, 7.42, 0.87, 0.85microM for OCl-AML3, THP1, MOLM13, HL60, KG1, NB4 cell respectively)[1].
  • SMILES
    O=C(O1)C=CC2=C1C=CC(NC3=CC(N4CCCC(NC(CBr)=O)C4)=NC5=NC=NN53)=C2
  • UNSPSC
    12131703