WRG-28

MedChem Express

WRG-28 [1913291-02-7]

10

1913291-02-7

Research Use Only

99.34

C21H18N2O5S

410.44

WRG-28 is a selective, extracellularly acting DDR2 allosteric inhibitor, with an IC 50 of 230 nM. WRG-28 inhibits tumor invasion, migration and tumor-supporting effects of cancer-associated fibroblasts (CAFs). WRG-28 inhibits metastatic breast tumor cell colonization in the lungs. WRG-28 also shows good activity of relieving rheumatoid arthritis in CAIA model of mice [1] [2] .

O=S(C1=CC=C(COC2=CC(OC3=CC(C=CC3=N4)=O)=C4C=C2)C=C1)(NCC)=O

-20°C,2°C to 8°C

12352200