
Immunohistochemistry of paraffin-embedded human endometrial cancer using CSB-PA11609A0Rb at dilution of 1:100
WT1 Antibody
CSB-PA11609A0RB
ApplicationsELISA, ImmunoHistoChemistry
Product group Antibodies
TargetWT1
Overview
- SupplierCusabio
- Product NameWT1 Antibody
- Delivery Days Customer20
- ApplicationsELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID7490
- Target nameWT1
- Target descriptionWT1 transcription factor
- Target synonymsAWT1; GUD; NPHS4; WAGR; Wilms tumor 1; Wilms tumor protein; WIT-2; WT33
- HostRabbit
- IsotypeIgG
- Protein IDP19544
- Protein NameWilms tumor protein
- Scientific DescriptionTranscription factor that plays an important role in cellular development and cell survival. Regulates the expression of numerous target genes, including EPO. Plays an essential role for development of the urogenital system. Recognizes and binds to the DNA sequence 5-CGCCCCCGC-3. It has a tumor suppressor as well as an oncogenic role in tumor formation. Function may be isoform-specific: isoforms lacking the KTS motif may act as transcription factors. Isoforms containing the KTS motif may bind mRNA and play a role in mRNA metabolism or splicing. Isoform 1 has lower affinity for DNA, and can bind RNA.
- Storage Instruction-20°C or -80°C
- UNSPSC12352203