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ProductsBack/WWP2 Antibody

Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA026168LA01HU at dilution of 1:100

Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA026168LA01HU at dilution of 1:100

Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA026168LA01HU at dilution of 1:100

WWP2 Antibody

CSB-PA026168LA01HU

ApplicationsELISA, ImmunoHistoChemistry

Product group Antibodies

ReactivityHuman

TargetWWP2

Overview

Supplier
Cusabio
Product Name
WWP2 Antibody
Delivery Days Customer
20
Applications
ELISA, ImmunoHistoChemistry
Certification
Research Use Only
Clonality
Polyclonal
Conjugate
Unconjugated
Gene ID11060
Target name
WWP2
Target description
WW domain containing E3 ubiquitin protein ligase 2
Target synonyms
AIP2, WWp2-like, NEDD4-like E3 ubiquitin-protein ligase WWP2, HECT-type E3 ubiquitin transferase WWP2, atrophin-1 interacting protein 2
Host
Rabbit
Isotype
IgG
Protein IDO00308
Protein Name
NEDD4-like E3 ubiquitin-protein ligase WWP2
Scientific Description
E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Polyubiquitinates POU5F1 by Lys-63-linked conjugation and promotes it to proteasomal degradation; in embryonic stem cells (ESCs) the ubiquitination is proposed to regulate POU5F1 protein level. Ubiquitinates EGR2 and promotes it to proteasomal degradation; in T-cells the ubiquitination inhibits activation-induced cell death. Ubiquitinates SLC11A2; the ubiquitination is enhanced by presence of NDFIP1 and NDFIP2. Ubiquitinates RPB1 and promotes it to proteasomal degradation.
Reactivity
Human
Storage Instruction
-20°C or -80°C
UNSPSC
41116161

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