WX8 [232935-92-1]

TargetMol Chemicals

WX8 [232935-92-1]

9

Research Use Only

C22H22N8O

414.46

WX8 (Ro 91-4714) is an ATP-competitive inhibitor of PIKFYVE, displaying Kd values of 0.9 nM for PIKFYVE and 340 nM for PIP4K2C. This compound inhibits lysosomal fission without affecting homotypic lysosome fusion. WX8 (Ro 91-4714) is applicable in research on autophagy-dependent cancers.

N(=CC1=CNC=2C=CC=CC12)NC=3N=C(N=C(N3)N4CCOCC4)NC=5C=CC=CC5

-20°C

12352200