WYE-354

MedChem Express

WYE-354 [1062169-56-5]

10

1062169-56-5

Research Use Only

98.04

C24H29N7O5

495.53

WYE-354 is an ATP-competitive mTOR inhibitor with an IC 50 of 5 nM. WYE-354 also inhibits PI3Kalpha and PI3Kgamma with IC 50 s of 1.89 microM and 7.37 microM, respectively. WYE-354 inhibits both mTORC1 and mTORC2 . WYE-354 induces autophagy activation in vitro [3] .

COC(NC1=CC=C(C=C1)C2=NC3=C(C(N4CCOCC4)=N2)C=NN3C5CCN(CC5)C(OC)=O)=O

-20°C,2°C to 8°C

12352200