WZ811 [55778-02-4]

MedChem Express

WZ811 [55778-02-4]

10

55778-02-4

Research Use Only

99.80

C18H18N4

290.36

WZ811 is an orally active, highly potent competitive antagonist of CXCR4. WZ811 efficiently inhibits CXCR4/SDF-1 (or CXCL12)-mediated modulation of cAMP levels (EC50=1.2 nM) and SDF-1 induced Matrigel invasion in cells (EC50=5.2 nM)[1].

C1(CNC2=NC=CC=C2)=CC=C(CNC3=NC=CC=C3)C=C1

-20°C,2°C to 8°C

12352200