XAP044 [196928-50-4]

MedChem Express

XAP044 [196928-50-4]

10

196928-50-4

Research Use Only

99.99

h302, h315, h319, h335

C15H9IO4

380.13

XAP044 is a potent and selective antagonist of mGlu7. The metabotropic glutamate receptor subtype 7 (mGlu7) is an important presynaptic regulator of neurotransmission in the mammalian CNS. XAP044 demonstrates good brain exposure and wide spectrum anti-stress and antidepressant- and anxiolytic-like efficacy in rodent behavioral paradigms[1].

O=C1C2=CC=C(O)C=C2OC=C1OC3=CC=C(I)C=C3

2°C to 8°C

12352200