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XAV-939 [284028-89-3]
T1878
Overview
- SupplierTargetMol Chemicals
- Product NameXAV-939 [284028-89-3]
- Delivery Days Customer4
- CAS Number284028-89-3
- Category SupplierChemical
- CertificationResearch Use Only
- Chemical NameXAV-939
- Molecular FormulaC14H11F3N2OS
- Molecular Weight312.31
- Scientific DescriptionXAV-939 (NVP-XAV939) is a Tankyrase (TNKS) inhibitor that inhibits TNKS1 and TNKS2 (IC50=11/4 nM). XAV-939 selectively inhibits Wnt/beta-catenin-mediated transcription.
- Shelf life instruction3 years
- SMILESFC(F)(F)C1=CC=C(C=C1)C1=NC(=O)C2=C(CCSC2)N1
- Storage Instruction-20°C
- UNSPSC12352200
References
- Huang SM, et al. Tankyrase inhibition stabilizes axin and antagonizes Wnt signalling. Nature. 2009 Oct 1;461(7264):614-20.Read more