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XAV-939

T1878
TargetMol Chemicals
CAS Number284028-89-3
Product group Chemicals
Molecular Weight312.31
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    XAV-939
  • Delivery Days Customer
    4
  • CAS Number
    284028-89-3
  • Category Supplier
    Chemical
  • Chemical Name
    XAV-939
  • Molecular Formula
    C14H11F3N2OS
  • Molecular Weight
    312.31
  • Scientific Description
    XAV-939 (NVP-XAV939) is a Tankyrase (TNKS) inhibitor that inhibits TNKS1 and TNKS2 (IC50=11/4 nM). XAV-939 selectively inhibits Wnt/bèta-catenin-mediated transcription.
  • Shelf life instruction
    3 years
  • SMILES
    O=C1N=C(NC2=C1CSCC2)C3=CC=C(C(F)(F)F)C=C3
  • Storage Instruction
    -20°
  • UNSPSC
    12352200

References

  • Huang SM, et al. Tankyrase inhibition stabilizes axin and antagonizes Wnt signalling. Nature. 2009 Oct 1;461(7264):614-20.
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