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XEN445 [1515856-92-4]

HY-12246
MedChem Express
CAS Number1515856-92-4
Product group Chemicals
Estimated Purity99.85
Molecular Weight366.33
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Overview

  • Supplier
    MedChem Express
  • Product Name
    XEN445 [1515856-92-4]
  • Delivery Days Customer
    10
  • CAS Number
    1515856-92-4
  • Certification
    Research Use Only
  • Estimated Purity
    99.85
  • Molecular Formula
    C18H17F3N2O3
  • Molecular Weight
    366.33
  • Scientific Description
    XEN445 is an endothelial lipase (EL) inhibitor with an IC50 of 0.237 uM. It has excellent ADME and PK activity and can increase the concentration of high-density lipoprotein cholesterol in mouse plasma.
  • SMILES
    O=C(O)C1=CC(C(F)(F)F)=CC=C1N2C[C@@H](OCC3=NC=CC=C3)CC2
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200

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