Xestospongin C
HY-103312
Overview
- SupplierMedChem Express
- Product NameXestospongin C [88903-69-9]
- Delivery Days Customer10
- CAS Number88903-69-9
- CertificationResearch Use Only
- Estimated Purity99.0
- Molecular FormulaC28H50N2O2
- Molecular Weight446.71
- Scientific DescriptionXestospongin C ((-)-Xestospongin C) is a selective, reversible inositol 1,4,5-trisphosphate receptor (IP3R) inhibitor. Xestospongin C acts as an inhibitor of the sarcoplasmic/endoplasmic reticulum Ca 2+ ATPase (SERCA) pump of internal stores. Xestospongin C blocks IP3-induced Ca 2+ release from cerebellar microsomes with an IC 50 of 358 nM. Xestospongin C is a valuable tool for investigating the structure and function of IP3Rs and Ca 2+ signaling in neuronal and nonneuronal cells [1] [2] [3] .
- SMILES[H][C@]1([C@](CCCCCC[C@@](CCN2CCC3)([H])O[C@@]2([H])[C@]3([H])CCCCCC4)([H])CCC5)N5CC[C@]4([H])O1
- Storage Instruction-20°C
- UNSPSC12352200