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Xestospongin C

HY-103312
MedChem Express
CAS Number88903-69-9
Product group Chemicals
Estimated Purity99.0
Molecular Weight446.71
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Xestospongin C [88903-69-9]
  • Delivery Days Customer
    10
  • CAS Number
    88903-69-9
  • Certification
    Research Use Only
  • Estimated Purity
    99.0
  • Molecular Formula
    C28H50N2O2
  • Molecular Weight
    446.71
  • Scientific Description
    Xestospongin C ((-)-Xestospongin C) is a selective, reversible inositol 1,4,5-trisphosphate receptor (IP3R) inhibitor. Xestospongin C acts as an inhibitor of the sarcoplasmic/endoplasmic reticulum Ca 2+ ATPase (SERCA) pump of internal stores. Xestospongin C blocks IP3-induced Ca 2+ release from cerebellar microsomes with an IC 50 of 358 nM. Xestospongin C is a valuable tool for investigating the structure and function of IP3Rs and Ca 2+ signaling in neuronal and nonneuronal cells [1] [2] [3] .
  • SMILES
    [H][C@]1([C@](CCCCCC[C@@](CCN2CCC3)([H])O[C@@]2([H])[C@]3([H])CCCCCC4)([H])CCC5)N5CC[C@]4([H])O1
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200