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Xevinapant [1071992-99-8]

Xevinapant [1071992-99-8]

T6763
TargetMol Chemicals
CAS Number1071992-99-8
Product group Chemicals
Estimated Purity99.77%
Molecular Weight561.71
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    Xevinapant [1071992-99-8]
  • Delivery Days Customer
    9
  • CAS Number
    1071992-99-8
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    Xevinapant
  • Estimated Purity
    99.77%
  • Molecular Formula
    C32H43N5O4
  • Molecular Weight
    561.71
  • Scientific Description
    Xevinapant (Debio-1143) is a potent Smac mimetic and an antagonist of IAP (inhibitor of apoptosis protein via E3 ubiquitin ligase), binding to XIAP-BIR3, cIAP1-BIR3 and cIAP2-BIR3 with Ki of 66.4 nM, 1.9 nM, and 5.1 nM, 50- to 100-fold higher affinities than the Smac AVPI peptide. Phase 1.
  • Shelf life instruction
    3 years
  • SMILES
    CN[C@@H](C)C(=O)N[C@H]1CN(CC[C@H]2CC[C@H](N2C1=O)C(=O)NC(c1ccccc1)c1ccccc1)C(=O)CC(C)C
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

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