Xevinapant [1071992-99-8]
T6763
CAS Number1071992-99-8
Product group Chemicals
Estimated Purity99.77%
Molecular Weight561.71
Overview
- SupplierTargetMol Chemicals
- Product NameXevinapant [1071992-99-8]
- Delivery Days Customer9
- CAS Number1071992-99-8
- CertificationResearch Use Only
- Chemical NameXevinapant
- Estimated Purity99.77%
- Molecular FormulaC32H43N5O4
- Molecular Weight561.71
- Scientific DescriptionXevinapant (Debio-1143) is a potent Smac mimetic and an antagonist of IAP (inhibitor of apoptosis protein via E3 ubiquitin ligase), binding to XIAP-BIR3, cIAP1-BIR3 and cIAP2-BIR3 with Ki of 66.4 nM, 1.9 nM, and 5.1 nM, 50- to 100-fold higher affinities than the Smac AVPI peptide. Phase 1.
- Shelf life instruction3 years
- SMILESCN[C@@H](C)C(=O)N[C@H]1CN(CC[C@H]2CC[C@H](N2C1=O)C(=O)NC(c1ccccc1)c1ccccc1)C(=O)CC(C)C
- Storage Instruction-20°C
- UNSPSC12352200
MSDS
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