XL-784 (free base) [1356992-21-6]

MedChem Express

XL-784 (free base) [1356992-21-6]

10

1356992-21-6

Research Use Only

C21H22ClF2N3O8S

549.93

XL-784 free base is a selective matrix metalloproteinases (MMP) inhibitor, with IC50s of ~1900, 0.81, 120, 10.8, 18, 0.56 nM for MMP-1, MMP-2, MMP-3, MMP-8, MMP-9 and MMP-13, respectively[1][2].

O=C(N1CC(C(NO)=O)N(S(=O)(C2=CC(F)=C(OC3=CC=C(Cl)C=C3)C(F)=C2)=O)CC1)OCCOC

12352200