XL177A

MedChem Express

XL177A [2417089-74-6]

10

2417089-74-6

Research Use Only

99.60

C48H57ClN8O5

861.47

XL177A is a highly potent and selective irreversible USP7 inhibitor with an IC 50 of 0.34 nM. XL177A elicits cancer cell killing through a p53-dependent mechanism [1] .

O=C(C(C=CC1=C2Cl)=CC1=NC3=C2CCCC3)NCCC[C@@H](CC4=CC=CC=C4)C(N5CCC(CN6C=NC7=C(C=CC(NC(CCN8CCN(C)CC8)=O)=C7)C6=O)(O)CC5)=O

-20°C,2°C to 8°C

12352200