XL228 [898280-07-4]

MedChem Express

XL228 [898280-07-4]

10

898280-07-4

Research Use Only

99.64

C22H31N9O

437.54

XL228 is a multi-targeted tyrosine kinase inhibitor with IC50s of 5, 3.1, 1.6, 6.1, 2 nM for Bcr-Abl, Aurora A, IGF-1R, Src and Lyn, respectively.

CN1CCN(C2=CC(NC3=NNC(C4CC4)=C3)=NC(NCC5=CC(C(C)C)=NO5)=N2)CC1

-20°C,2°C to 8°C

12352200