XY018 [1873358-87-2]

MedChem Express

XY018 [1873358-87-2]

5

1873358-87-2

Research Use Only

99.9%

C23H15F7N2O4

516.37

XY018 is a potent ROR-gamma-selective antagonist. XY018 inhibits ROR-gamma constitutive activity in 293T cells with high potency (EC50, 190 nM). XY018 binds to the ROR-gamma hydrophobic ligand binding domain (LBD).

OC(C(F)(F)F)(C1=CC(F)=C(C(C=C2)=CC=C2NC(CC(C=CC=C3)=C3[N](=O)=O)=O)C=C1)C(F)(F)F

2°C to 8°C,-20°C,-80°C

12352200