Xylitol-13C5
HY-W768347
Molecular Weight157.11
Product group Chemicals
Overview
- SupplierMedChem Express
- Product NameXylitol-13C5
- Delivery Days Customer999
- CertificationResearch Use Only
- Molecular Formula13C5H12O5
- Molecular Weight157.11
- Scientific DescriptionXylitol-13C5 (Xylite-13C5) is the 13C-labeled Xylitol (HY-N0538). Xylitol can be classified as a polyol and sugar alcohol, exhibiting inhibitory activity on cancer cell proliferation. It induces autophagy (Autophagy) and cell death in A549 cells by activating the autophagy signaling pathway, as evidenced by the increased expression of LC3-II and Atg5-Atg12 upon Xylitol treatment. Additionally, Xylitol inhibits acetaldehyde production by Candida species, thereby reducing their carcinogenic potential. In vivo, Xylitol induces alterations in the gut microbiota of mice, which may enhance cholesterol accumulation and upregulate hepatic ChREBP, while also slowing tumor growth in the B16F10 melanoma C57BL/6 mouse model[1][2][3][4].
- SMILESO[13CH2][13C@H](O)[13C@@H](O)[13C@H](O)[13CH2]O
- UNSPSC12352200