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Y-27632

Research Use Only
HY-10071
MedChem Express
CAS Number146986-50-7
DownloadMSDS
Product group Chemicals
Estimated Purity99.91
Molecular Weight247.34
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Y-27632 [146986-50-7]
  • Delivery Days Customer
    10
  • CAS Number
    146986-50-7
  • Certification
    Research Use Only
  • Estimated Purity
    99.91
  • Molecular Formula
    C14H21N3O
  • Molecular Weight
    247.34
  • Scientific Description
    Y-27632 is an orally active, ATP-competitive inhibitor of ROCK-I and ROCK-II, with Kis of 220 and 300 nM, respectively. Y-27632 attenuates Doxorubicin-induced apoptosis of human cardiac stem cells. Y-27632 also suppresses dissociation-induced apoptosis of murine prostate stem/progenitor cells. Y-27632 primes human induced pluripotent stem cells (hIPSCs) to selectively differentiate towards mesendodermal lineage via epithelial-mesenchymal transition-like modulation[1][2][3][4][5][6][7].
  • SMILES
    O=C([C@@H]1CC[C@]([C@H](N)C)([H])CC1)NC2=CC=NC=C2
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200