Y-27632 (hydrochloride hydrate) [331752-47-7]
HY-10071A
CAS Number331752-47-7
Product group Chemicals
Molecular Weight338.27
Overview
- SupplierMedChem Express
- Product NameY-27632 (hydrochloride hydrate) [331752-47-7]
- Delivery Days Customer5
- CAS Number331752-47-7
- CertificationResearch Use Only
- Molecular FormulaC14H25Cl2N3O2
- Molecular Weight338.27
- Scientific DescriptionY-27632 hydrochloride hydrate is an orally active, ATP-competitive inhibitor of ROCK-I and ROCK-II, with Kis of 220 and 300 nM, respectively. Y-27632 hydrochloride hydrate attenuates Doxorubicin-induced apoptosis of human cardiac stem cells. Y-27632 hydrochloride hydrate also suppresses dissociation-induced apoptosis of murine prostate stem/progenitor cells. Y-27632 hydrochloride hydrate primes human induced pluripotent stem cells (hIPSCs) to selectively differentiate towards mesendodermal lineage via epithelial-mesenchymal transition-like modulation[1][2][3][4][5][6][7].
- SMILESO=C([C@H]1CC[C@](CC1)([H])[C@H](N)C)NC2=CC=NC=C2.Cl.O.Cl
- UNSPSC12352200
MSDS
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Molecular Weight338.27
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Molecular Weight338.27
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