Y-29794 (tosylate) [143984-17-2]
HY-15113A
CAS Number143984-17-2
Product group Chemicals
Molecular Weight590.86
Overview
- SupplierMedChem Express
- Product NameY-29794 (tosylate) [143984-17-2]
- Delivery Days Customer5
- CAS Number143984-17-2
- CertificationResearch Use Only
- Molecular FormulaC30H42N2O4S3
- Molecular Weight590.86
- Scientific DescriptionY-29794 tosylate is a selective, orally active inhibitor for non-peptide prolyl endopeptidase (PREP), with an IC50 of 3 nM and a Ki of 0.95 nM. Y-29794 tosylate enhances the effect of thyrotropin-releasing hormone (TRH) on the release of ACh in the rat hippocampus, exhibits potential neuroprotective efficacy. Y-29794 tosylate exhibits anticancer activity through inhibition of the IRS1-AKT-mTORC1 pathway. Y-29794 tosylate penetrates the brain-blood barrier (BBB)[1][2].
- SMILESO=C(C1=CC=C(C(C)C)N=C1SCCCCCCCCN(C)C)C2=CC=CS2.O=S(C3=CC=C(C)C=C3)(O)=O
- UNSPSC12352200