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YF-2 (hydrochloride)

HY-16531A
MedChem Express
CAS Number1312005-62-1
Product group Chemicals
Estimated Purity99.61
Molecular Weight467.31
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Overview

  • Supplier
    MedChem Express
  • Product Name
    YF-2 (hydrochloride) [1312005-62-1]
  • Delivery Days Customer
    10
  • CAS Number
    1312005-62-1
  • Certification
    Research Use Only
  • Estimated Purity
    99.61
  • Molecular Formula
    C20H23Cl2F3N2O3
  • Molecular Weight
    467.31
  • Scientific Description
    YF-2 hydrochloride is a highly selective, blood-brain-barrier permeable histone acetyltransferase activator, acetylates H3 in the hippocampus, with EC 50 s of 2.75 microM, 29.04 microM and 49.31 microM for CBP, PCAF, and GCN5, respectively, shows no effect on HDAC. Anti-cancer and anti-Alzheimers disease [1] .
  • SMILES
    O=C(NC1=CC=C(Cl)C(C(F)(F)F)=C1)C2=C(OCC)C=CC=C2OCCN(C)C.Cl
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200