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YF-2 (hydrochloride)

HY-16531A
MedChem Express
CAS Number1312005-62-1
DownloadMSDS
Product group Chemicals
Estimated Purity99.61
Molecular Weight467.31
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Overview

  • Supplier
    MedChem Express
  • Product Name
    YF-2 (hydrochloride) [1312005-62-1]
  • Delivery Days Customer
    10
  • CAS Number
    1312005-62-1
  • Certification
    Research Use Only
  • Estimated Purity
    99.61
  • Molecular Formula
    C20H23Cl2F3N2O3
  • Molecular Weight
    467.31
  • Scientific Description
    YF-2 hydrochloride is a highly selective, blood-brain-barrier permeable histone acetyltransferase activator, acetylates H3 in the hippocampus, with EC50s of 2.75 microM, 29.04 microM and 49.31 microM for CBP, PCAF, and GCN5, respectively, shows no effect on HDAC. Anti-cancer and anti-Alzheimers disease[1].
  • SMILES
    O=C(NC1=CC=C(Cl)C(C(F)(F)F)=C1)C2=C(OCC)C=CC=C2OCCN(C)C.Cl
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200