YF-452 [1951466-83-3]
HY-120200
CAS Number1951466-83-3
Product group Chemicals
Molecular Weight452.39
Overview
- SupplierMedChem Express
- Product NameYF-452 [1951466-83-3]
- Delivery Days Customer10
- CAS Number1951466-83-3
- CertificationResearch Use Only
- Molecular FormulaC24H26BrN3O
- Molecular Weight452.39
- Scientific DescriptionYF-452 is a potent inhibitor of vascular endothelial growth factor receptor 2 (VEGFR2). YF-452 remarkably inhibits the migration, invasion and tube-like structure formation of human umbilical vein endothelial cells (HUVECs) with little toxicity. YF-452 inhibits VEGF-induced phosphorylation of VEGFR2 kinase and the downstream protein kinases including extracellular signal regulated kinase (ERK), focal adhesion kinase (FAK) and Src. YF-452 is a potential antiangiogenic agent candidate for cancer research[1].
- SMILESBrC1=CC=C(CN(C2=C3C=CC=C2)C4=C3CCN(C4)C(CN5CCCC5)=O)C=C1
- UNSPSC12352200
MSDS
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Product group Chemicals
YF-452 [1951466-83-3]T29173
CAS Number1951466-83-3
Molecular Weight452.39
- SizePrice
Product group Chemicals
YF-452ORB1698956
CAS Number1951466-83-3
Estimated Purity98%
Molecular Weight452.39
- SizePrice