YK 3-237
M7500
CAS Number1215281-19-8
Product group Chemicals
Molecular Weight372.18
Overview
- SupplierAbMole BioScience
- Product NameYK 3-237
- Delivery Days Customer9
- CAS Number1215281-19-8
- Category SupplierChemical
- CertificationResearch Use Only
- Molecular FormulaC19H21BO7
- Molecular Weight372.18
- Scientific DescriptionYK 3-237 is a boronic acid chalcone analog of combretastatin a4 (CA-4) and a SIRT1 activator that targets mutant p53. YK 3-237 can reduce the acetylation of mutant p53 protein by activating the SIRT1 enzyme, resulting in a significant decrease in the level of mutant p53 protein. YK-3-237 showed antiproliferative activity against tumor cells containing mutant p53 protein.
- SMILESCOC1=C(OC)C(=CC(=C1)C(=O)/C=C/C2=CC=C(OC)C(=C2)B(O)O)OC
- UNSPSC12352200