Bio-Connect

YL5084 [2440199-73-3]

HY-149930
MedChem Express
CAS Number2440199-73-3
Product group Chemicals
Molecular Weight600.71
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Overview

  • Supplier
    MedChem Express
  • Product Name
    YL5084 [2440199-73-3]
  • Delivery Days Customer
    10
  • CAS Number
    2440199-73-3
  • Certification
    Research Use Only
  • Molecular Formula
    C35H36N8O2
  • Molecular Weight
    600.71
  • Scientific Description
    YL5084, a covalent JNK inhibitor, exhibits selectivity for JNK2 and JNK3 over JNK1 with IC50s of 70 nM, 84 nM and 2173 nM, respectively. YL5084 exhibits JNK2-independent antiproliferative effects and induces apoptosis in a JNK2-independent manner[1].
  • SMILES
    O=C(C1=CC=C(C=C1)NC(/C=C/CN(C)C)=O)N(C[C@@H]2C)C[C@H]2NC3=NC=CC(C4=C(C=CC=C5)N5N=C4C6=CC=CC=C6)=N3
  • UNSPSC
    12131703