YM-202074 (fumarate) [299900-84-8]
HY-103556
CAS Number299900-84-8
Product group Chemicals
Molecular Weight1177.34
Overview
- SupplierMedChem Express
- Product NameYM-202074 (fumarate) [299900-84-8]
- Delivery Days Customer5
- CAS Number299900-84-8
- CertificationResearch Use Only
- Molecular FormulaC56H72N8O16S2
- Molecular Weight1177.34
- Scientific DescriptionYM-202074 fumarate is a selective, allosteric metabotropic glutamate receptor type 1 (mGluR1) antagonist with high affinity. YM-202074 fumarate binds to the allosteric site of rat mGluR1 with a Ki of 4.8 nM. YM-202074 fumarate also inhibits mGluR1-mediated inositol phosphate production in rat cerebellar granule cells with an IC50 of 8.6 nM. YM-202074 fumarate has potent neuroprotective effects in transient MCA (tMCA) occlusion rat models[1].
- SMILESOC(/C=C/C(O)=O)=O.CN(C1CCCCC1)C(C2=CN3C4=CC(CN(C)CCOC)=CC=C4N=C3S2)=O.OC(/C=C/C(O)=O)=O.OC(/C=C/C(O)=O)=O.CN(C5CCCCC5)C(C6=CN7C8=CC(CN(C)CCOC)=CC=C8N=C7S6)=O
- UNSPSC12352200
MSDS
Related products
Product group Chemicals
YM 202074ORB1703907
CAS Number299900-84-8
Estimated Purity98%
Molecular Weight588.68
- SizePrice
![YM 202074 [299900-84-8]](https://www.targetmol.com/group3/M00/02/62/CgoaEWY7K_OEAJWlAAAAABAMZqk606.png)
Product group Chemicals
YM 202074 [299900-84-8]T23544
CAS Number299900-84-8
Molecular Weight588.68
- SizePrice