YM-230888 [446257-23-4]
HY-107510
CAS Number446257-23-4
Product group Chemicals
Molecular Weight360.52
Overview
- SupplierMedChem Express
- Product NameYM-230888 [446257-23-4]
- Delivery Days Customer9
- CAS Number446257-23-4
- CertificationResearch Use Only
- Molecular FormulaC19H28N4OS
- Molecular Weight360.52
- Scientific DescriptionYM-230888 is an orally active, selective and allosteric mGlu1 receptor antagonist with a Ki of 13 nM. YM-230888 inhibits mGlu1-mediated inositol phosphate production in rat cerebellar granule cells with an IC50 of 13 nM. YM-230888 shows antinociceptive response in Streptozotocin (HY-13753)-induced hyperalgesia models. YM-230888 significantly reduces pain parameters in complete Freunds adjuvant (HY-153808)-induced arthritic pain models[1].
- SMILESC1(NC2CCCCCC2)=C3C(SC(CNC[C@H]4CCCO4)=C3)=NC=N1
- UNSPSC12352200
MSDS
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Product group Chemicals
YM 230888 [446257-23-4]T23545
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