YM-341619 [643082-52-4]

MedChem Express

YM-341619 [643082-52-4]

5

643082-52-4

Research Use Only

98.01

C22H21F3N6O2

458.44

YM-341619 (AS1617612) is a potent and orally active STAT6 inhibitor with an IC50 of 0.70 nM. YM-341619 inhibits Th2 differentiation in mouse spleen T cells induced by IL-4 (IC50=0.28 nM) without affecting Th1 cell differentiation[1]. YM-341619 is a promising compound for the the research of allergic diseases, such as allergic asthma[2].

O=C(C1=CN=C(NC2=CC=C(N3CCOCC3)C=C2)N=C1NCC4=C(F)C=CC(F)=C4F)N

-20°C,2°C to 8°C

12352200