Bio-Connect

YM114 [153608-99-2]

HY-106909A
MedChem Express
CAS Number153608-99-2
Product group Chemicals
Molecular Weight303.79
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Overview

  • Supplier
    MedChem Express
  • Product Name
    YM114 [153608-99-2]
  • Delivery Days Customer
    9
  • CAS Number
    153608-99-2
  • Certification
    Research Use Only
  • Molecular Formula
    C16H18ClN3O
  • Molecular Weight
    303.79
  • Scientific Description
    YM114 (KAE-393) is a highly potent and selective (5-HT)3-receptor antagonist that does not affect Veratridine (HY-N6691)- or electrical stimulation-induced bradycardia in anesthetized rats. YM114 inhibits 2-methyl-5-HT (HY-19358)-induced Bezold-Jarisch reflex, which originates from (5-HT)3-receptor located on the endings of vagal afferent nerves in the heart[1].
  • SMILES
    O=C([C@H]1CC2=C(N=CN2)CC1)N3C4=CC=CC=C4CC3.Cl
  • UNSPSC
    12352200